发明授权
- 专利标题： PHARMACEUTICAL COMPOSITION STABILIZED WITH A BASIC AGENT
- 专利标题（中）： 药物组合物用碱性介质上稳定
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申请号： EP96942588.3申请日： 1996-12-20
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公开(公告)号： EP0814782B1公开(公告)日： 2002-11-27
- 发明人: MURAMATSU, Toyojiro , MASHITA, Katsumi , SHINODA, Yasuo , SASSA, Hironori , KAWASHIMA, Hiroyuki , TANIZAWA, Yoshio , TAKEUCHI, Hideatsu
- 申请人： KOWA COMPANY LTD. , NISSAN CHEMICAL INDUSTRIES, LIMITED
- 申请人地址： 6-29, Nishiki 3-chome, Naka-ku Nagoya-shi Aichi-ken, 460-8625 JP
- 专利权人： KOWA COMPANY LTD.,NISSAN CHEMICAL INDUSTRIES, LIMITED
- 当前专利权人： KOWA COMPANY LTD.,NISSAN CHEMICAL INDUSTRIES, LIMITED
- 当前专利权人地址： 6-29, Nishiki 3-chome, Naka-ku Nagoya-shi Aichi-ken, 460-8625 JP
- 代理机构： Silverman, Warren
- 优先权： JP35465495 19951222
- 国际公布： WO97023200 19970703
- 主分类号： A61K9/20
- IPC分类号： A61K9/20 ; A61K31/47
摘要：
Disclosed is a pharmaceutical composition comprising (E)-3,5-dihydroxy-7-[4'-4'-fluorophenyl-2'-cyclopropyl-quinolin-3'-yl]-6-heptenoic acid, or its salt or ester, of which the aqueous solution or dispersion has a pH of from 7 to 8. The composition has good time-dependent stability and has no change in its outward appearance even after having been stored long.
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