发明公开
- 专利标题： CD6 LIGAND
- 专利标题（中）： CD6 -LIGAND
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申请号： EP96913873.0申请日： 1996-04-29
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公开(公告)号： EP0830373A1公开(公告)日： 1998-03-25
- 发明人: HAYNES, Barton, F. , ARUFFO, Alejandro , PATEL, Dhavalkumar , BOWEN, Michael, A. , MARQUARDT, Hans
- 申请人： DUKE UNIVERSITY , Bristol-Myers Squibb Company
- 申请人地址： 230 North Building, Research Drive, Box 90083 Durham, North Carolina 27708-0083 US
- 专利权人： DUKE UNIVERSITY,Bristol-Myers Squibb Company
- 当前专利权人： DUKE UNIVERSITY,Bristol-Myers Squibb Company
- 当前专利权人地址： 230 North Building, Research Drive, Box 90083 Durham, North Carolina 27708-0083 US
- 代理机构： Kinzebach, Werner, Dr., et al
- 优先权： US19950432016 19950501
- 国际公布： WO1996034880 19961107
- 主分类号： G01N33
- IPC分类号： G01N33 ; A61K38 ; A61P37 ; C07K14 ; C07K16 ; C12N5 ; C12N15 ; C12P21 ; C12R1
摘要：
The present invention relates, in general, to CD6 and, in particular, to a CD6 ligand present on the surface of thymic epithelial cells, monocytes, activated T cells and a variety of other cell types. The invention further relates to methods of inhibiting the interaction of CD6 and the CD6 ligand, and to methods of screening compounds for their ability to inhibit that interaction.
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