发明授权
- 专利标题： VEGF-RELATED PROTEIN
- 专利标题（中）： VEGF相关蛋白
-
申请号： EP96931450.9申请日： 1996-08-30
-
公开(公告)号： EP0848755B2公开(公告)日： 2011-02-09
- 发明人: LEE, James , WOOD, William
- 申请人： Genentech, Inc.
- 申请人地址： 1 DNA Way South San Francisco CA 94080-4990 US
- 专利权人： Genentech, Inc.
- 当前专利权人： Genentech, Inc.
- 当前专利权人地址： 1 DNA Way South San Francisco CA 94080-4990 US
- 代理机构： Kiddle, Simon John
- 优先权： US3491 19950908
- 国际公布： WO1997009427 19970313
- 主分类号： C12N15/19
- IPC分类号： C12N15/19 ; C07K14/52 ; C07K19/00 ; C07K16/24 ; A61K38/19 ; G01N33/50
摘要：
A human VEGF-related protein (VRP) has been identified and isolated that binds to, and stimulates the phosphorylation of, the receptor tyrosine kinase Flt4. The VRP is postulated to be a third member of the VEGF protein family. Also provided are antibodies that bind to VRP and neutralize a biological activity of VRP, compositions containing the VRP or antibody, methods of use, chimeric polypeptides, and a signal polypeptide for VRP.
公开/授权文献
- EP0848755B9 VEGF-RELATED PROTEIN 公开/授权日：2004-02-04
信息查询
IPC分类:
