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公开(公告)号:EP4426691A1
公开(公告)日:2024-09-11
申请号:EP22822795.5
申请日:2022-11-04
申请人: Genentech, Inc.
发明人: HUESTIS, Malcolm , LAMBRECHT, Michael John , LIANG, Jun , UNG, Man Un , WANG, Xiaojing , ZBIEG, Jason Robert , ZHU, Bing-Yan , BARTON, Lisa Marie , BROCCATELLI, Fabio , CASTANEDO, Georgette Marie , JAKALIAN, Araz , LAROUCHE-GAUTHIER, Robin , YADAV, Arun
IPC分类号: C07D405/14 , A61K31/4196 , A61P35/00
CPC分类号: C07D405/14
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公开(公告)号:EP4423713A1
公开(公告)日:2024-09-04
申请号:EP22814235.2
申请日:2022-10-26
申请人: Genentech, Inc.
IPC分类号: G06T7/00
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公开(公告)号:EP4423256A2
公开(公告)日:2024-09-04
申请号:EP22826273.9
申请日:2022-10-27
申请人: Genentech, Inc.
发明人: GURUNG, Hem Raj , HALEY, Benjamin Joseph , HEIDERSBACH, Amy Jeane , LI, Juan , ROSE, Christopher Michael , TONG, Ann-Jay , BLANCHETTE, Craig , CHAN, Pamela Pui Fung , DARWISH, Martine Abraham
CPC分类号: C12N5/0694 , C07K14/70539 , C07K14/47 , A61K39/0011 , A61P35/00 , A61K39/001164 , A61K39/001104
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公开(公告)号:EP4423056A1
公开(公告)日:2024-09-04
申请号:EP22818156.6
申请日:2022-10-26
申请人: GENENTECH, INC.
发明人: WONG, Nicholas , GOSSELIN, Francis
IPC分类号: C07C229/16 , C07B59/00
CPC分类号: C07C227/08 , C07C2601/1420170501 , C07C227/16 , C07C227/18
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公开(公告)号:EP4229196B1
公开(公告)日:2024-08-28
申请号:EP21802555.9
申请日:2021-10-14
IPC分类号: C12N15/10 , C12Q1/6851
CPC分类号: C12N15/1062 , C12Q1/6851 , G16B25/00 , G16B35/00
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公开(公告)号:EP3303386B1
公开(公告)日:2024-08-28
申请号:EP16728559.2
申请日:2016-06-02
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公开(公告)号:EP4365189A3
公开(公告)日:2024-08-14
申请号:EP24160370.3
申请日:2008-07-08
申请人: GENENTECH, INC.
发明人: KAO, Yung-hsiang , LAIRD, Michael W. , SCHMIDT, Melody Trexler , WONG, Rita L. , HEWITT, Daniel P.
CPC分类号: A61K39/39591 , C07K1/14 , C07K2317/2420130101 , C07K16/2887 , A61P37/02 , A61P5/00
摘要: The invention concerns methods and means for preventing the reduction of disulfide bonds during the recombinant production of disulfide-containing polypeptides. In particular, the invention concerns the prevention of disulfide bond reduction during harvesting of disulfide-containing polypeptides, including antibodies, from recombinant host cell cultures.
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公开(公告)号:EP4402469A1
公开(公告)日:2024-07-24
申请号:EP22786203.4
申请日:2022-09-15
申请人: Genentech, Inc.
CPC分类号: G01N33/5014 , G01N33/6806 , G01N2560/0020130101 , G01N2570/0020130101 , G01N2458/1520130101
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公开(公告)号:EP4396223A1
公开(公告)日:2024-07-10
申请号:EP22777525.1
申请日:2022-08-29
申请人: Genentech, Inc.
IPC分类号: C07K16/18
CPC分类号: C07K16/18 , C07K2317/3120130101
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