发明授权
EP0853628B1 NEUE PHOTOLABILE 8-SUBSTITUIERTE CYCLISCHE NUCLEOTIDESTER, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG
失效
新的照片不稳定8取代环NUCLEOTIDESTER，其制造方法相同，它们的用途
- 专利标题： NEUE PHOTOLABILE 8-SUBSTITUIERTE CYCLISCHE NUCLEOTIDESTER, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG
- 专利标题（英）： Photolabile 8-substituted cyclic nucleotide esters, methods of preparing them and their use
- 专利标题（中）： 新的照片不稳定8取代环NUCLEOTIDESTER，其制造方法相同，它们的用途
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申请号： EP96927617.9申请日： 1996-07-29
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公开(公告)号： EP0853628B1公开(公告)日： 2002-10-02
- 发明人: HAGEN, Volker , KAUPP, Ulrich, Benjamin
- 申请人： Forschungsverbund Berlin e.V. , Forschungszentrum Jülich GmbH
- 申请人地址： Rudower Chaussee 5 12489 Berlin DE
- 专利权人： Forschungsverbund Berlin e.V.,Forschungszentrum Jülich GmbH
- 当前专利权人： Forschungsverbund Berlin e.V.,Forschungszentrum Jülich GmbH
- 当前专利权人地址： Rudower Chaussee 5 12489 Berlin DE
- 代理机构： Gulde, Klaus W., Dipl.-Chem.
- 优先权： DE19529025 19950728
- 国际公布： WO97005155 19970213
- 主分类号： C07H19/20
- IPC分类号： C07H19/20
摘要：
The invention concerns photolabile 8-substituted guanosine-3',5'-cyclomonophosphate esters and 8-substituted adenosine-3',5'-cyclomonophosphate esters of formula (I) and methods of preparing these compounds by reacting the appropriate 8-substituted cyclic nucleotides with substituted diazoalkanes or substituted bromoalkanes or by substitution reactions at the 8-position of the appropriate 8-bromoguanosine-3',5'-cyclomonophosphate esters or 8-bromoadenosine-3',5'-cyclomonophosphate esters. The invention also concerns the use of such compounds. The compounds are suitable for use in the investigation of processes dependent on cyclic nucleotides. Fields of application are biological, biochemical, biophysical, physiological and medical research (formula (I)).
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