发明公开
- 专利标题： BIOLOGICALLY ACTIVE EPH FAMILY LIGANDS
- 专利标题（中）： Eph家族的生物学活性配体
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申请号： EP96937006.0申请日： 1996-10-25
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公开(公告)号： EP0859840A1公开(公告)日： 1998-08-26
- 发明人: DAVIS, Samuel , GALE, Nicholas, W. , YANCOPOULOS, George, D.
- 申请人： REGENERON PHARMACEUTICALS, INC.
- 申请人地址： 777 Old Saw Mill River Road Tarrytown, NY 10591-6707 US
- 专利权人： REGENERON PHARMACEUTICALS, INC.
- 当前专利权人： REGENERON PHARMACEUTICALS, INC.
- 当前专利权人地址： 777 Old Saw Mill River Road Tarrytown, NY 10591-6707 US
- 代理机构： Goldin, Douglas Michael
- 优先权： US19950007015P 19951025
- 国际公布： WO1997015667 19970501
- 主分类号： C12N15
- IPC分类号： C12N15 ; A61K31 ; A61K38 ; A61P25 ; C07K14 ; C07K16 ; C12N5 ; C12P21
摘要：
A novel ligand (Efl-6) that binds the Elk subfamily of Eph receptors is identified, and methods for making the soluble Elf-6 ligand in biologically active form is described. A cDNA clone encoding this novel protein enables production of the recombinant protein, which is useful to support neuronal and other Eph receptor-bearing cell populations.
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