发明授权
EP0863757B1 2-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE
失效
2-取代的芳基吡咯类，组合物这样的化合物含有它们及其用途
- 专利标题： 2-SUBSTITUTED ARYL PYRROLES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE
- 专利标题（中）： 2-取代的芳基吡咯类，组合物这样的化合物含有它们及其用途
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申请号： EP96928097.3申请日： 1996-08-08
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公开(公告)号： EP0863757B1公开(公告)日： 2003-03-26
- 发明人: DE LASZLO, Stephen, E. , MANTLO, Nathan, B. , PONTICELLO, Gerald, S. , SELNICK, Harold, G. , LIVERTON, Nigel, J.
- 申请人： MERCK & CO., INC.
- 申请人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065 US
- 专利权人： MERCK & CO., INC.
- 当前专利权人： MERCK & CO., INC.
- 当前专利权人地址： 126 East Lincoln Avenue Rahway, New Jersey 07065 US
- 代理机构： Thompson, John Dr.
- 优先权： US2093P 19950810; US14181P 19960326; GB9607254 19960404; GB9609264 19960502
- 国际公布： WO97005877 19970220
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; A61K31/50 ; A61K31/445 ; A61K31/495 ; A61K31/505 ; A61K31/535 ; C07D211/68 ; C07D211/80 ; C07D213/02 ; C07D239/02 ; C07D401/04 ; C07D401/14 ; C07D403/04
摘要：
The present invention addresses 2-substituted aryl pyrroles, as well as compositions containing such compounds and methods of treatment. Cytokine mediated diseases refers to diseases or conditions in which excessive or unregulated production or activity of one or more cytokines occurs. Interleukin-1 (IL-1), Interleukin-6 (IL-6), Interleukin-8 (IL-8) and Tumor Necrosis Factor (TNF) are cytokines which are involved.
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