发明公开
- 专利标题： VERFAHREN ZUR HERSTELLUNG VON PULVERFÖRMIGEN LUNGENSURFACTANT-ZUBEREITUNGEN
- 专利标题（英）： Process for the production of powdered pulmonary surfactant preparations
- 专利标题（中）： 用于生产粉末肺表面活性剂制剂
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申请号： EP97902186.0申请日： 1997-01-18
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公开(公告)号： EP0877602A1公开(公告)日： 1998-11-18
- 发明人: EISTETTER, Klaus
- 申请人： Byk Gulden Lomberg Chemische Fabrik GmbH
- 申请人地址： Byk-Gulden-Str. 2 78467 Konstanz DE
- 专利权人： Byk Gulden Lomberg Chemische Fabrik GmbH
- 当前专利权人： Byk Gulden Lomberg Chemische Fabrik GmbH
- 当前专利权人地址： Byk-Gulden-Str. 2 78467 Konstanz DE
- 优先权： DE19961002332 19960124; EP19960103442 19960306
- 国际公布： WO1997026863 19970731
- 主分类号： A61K9
- IPC分类号： A61K9 ; A61K31 ; A61K38 ; A61P11
摘要：
The invention concerns a process for the production of a powdered pulmonary surfactant preparation containing a hydrophobic protein serving as a pulmonary surfactant characterized by the fact that an organic solution or suspension containing a hydrophobic protein serving as a pulmonary surfactant and possibly other components is subject to spray drying. Powder preparations are obtained that exhibit very good stability under storage, are easy to reconstitute and which are also suitable for administration by inhalation.
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