发明公开
- 专利标题: ELECTROPHILIC KETONES FOR THE TREATMENT OF HERPESVIRUS INFECTIONS
- 专利标题(中): 电性酮类疱疹病毒感染的治疗
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申请号: EP97914954.0申请日: 1997-03-19
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公开(公告)号: EP0888322A2公开(公告)日: 1999-01-07
- 发明人: FLYNN, Daniel, L. , ZABLOCKI, Jeffery, A. , WILLIAMS, Kenneth , HOCKERMAN, Susan, L.
- 申请人: G.D. SEARLE & CO.
- 申请人地址: Corporate Patent Department P.O. Box 5110 Chicago IL 60680-5110 US
- 专利权人: G.D. SEARLE & CO.
- 当前专利权人: G.D. SEARLE & CO.
- 当前专利权人地址: Corporate Patent Department P.O. Box 5110 Chicago IL 60680-5110 US
- 代理机构: Beil, Hans Christoph, Dr,, et al
- 优先权: US19960620681 19960319
- 国际公布: WO1997034566 19970925
- 主分类号: C07D333
- IPC分类号: C07D333 ; A61K31 ; A61P31 ; C07C233 ; C07C235 ; C07C271 ; C07D209 ; C07D213 ; C07D241 ; C07D307
摘要:
A class of compounds is described which can be used for the treatment of viral infections. Compounds of particular interest are defined by Formula (II) wherein each of R?1, R2, and R3¿ is independently selected from hydrido, halo, and nitro; wherein R8 is selected from haloalkyl, optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, optionally substituted arylalkoxy and optionally substituted aryloxyalkyl; wherein Y is selected from fluoroalkyl, and (A); and wherein (R9) is alkylamino; or a pharmaceutically-acceptable salt or tautomer thereof.
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