发明公开
EP0912572A1 BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS
失效
双环杂芳族化合物作为酪氨酸激酶抑制剂蛋白质
- 专利标题： BICYCLIC HETEROAROMATIC COMPOUNDS AS PROTEIN TYROSINE KINASE INHIBITORS
- 专利标题（中）： 双环杂芳族化合物作为酪氨酸激酶抑制剂蛋白质
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申请号： EP97933661.0申请日： 1997-07-11
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公开(公告)号： EP0912572A1公开(公告)日： 1999-05-06
- 发明人: COCKERILL, George Stuart, Glaxo Wellcome plc , CARTER, Malcolm Clive, Glaxo Wellcome plc , GUNTRIP, Stephen Barry, Glaxo Wellcome plc , SMITH, Kathryn Jane, Glaxo Wellcome plc
- 申请人： GLAXO GROUP LIMITED
- 申请人地址： Glaxo Wellcome House Berkeley Avenue Greenford, Middlesex UB6 ONN GB
- 专利权人： GLAXO GROUP LIMITED
- 当前专利权人： GLAXO GROUP LIMITED
- 当前专利权人地址： Glaxo Wellcome House Berkeley Avenue Greenford, Middlesex UB6 ONN GB
- 代理机构： Reed, Michael Antony, et al
- 优先权： GB19960014756 19960713; GB19960025495 19961207
- 国际公布： WO1998002437 19980122
- 主分类号： A61K
- IPC分类号： A61K ; C07D ; A61K31 ; A61P17 ; A61P35 ; A61P43 ; C07C211 ; C07C217 ; C07C317 ; C07D471
摘要：
Substituted heteroaromatic compounds, and in particular substituted bicyclic heteroaromatic compounds in which one ring is a pyridine or pyrimidine of formula (I) are protein tyrosine kinase inhibitors. The compounds are described as are methods for their preparation, pharmaceutical compositions including such compounds and their use in medicine, for example in the treatment of cancer and psoriasis.
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