发明授权
- 专利标题： DIPEPTIDISCHE BENZAMIDINE ALS KININOGENASEN-INHIBITOREN
- 专利标题（英）： Dipeptide benzamidine as a kininogenase inhibitor
- 专利标题（中）： 二肽苄脒ALS抑制剂Kininogenases
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申请号： EP97934552.7申请日： 1997-07-29
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公开(公告)号： EP0918792B1公开(公告)日： 2000-09-27
- 发明人: BAUCKE, Dorit , LANGE, Udo , MACK, Helmut , PFEIFFER, Thomas , SEITZ, Werner , ZIERKE, Thomas , HÖFFKEN, Hans, Wolfgang , HORNBERGER, Wilfried
- 申请人： BASF AKTIENGESELLSCHAFT
- 申请人地址： 67056 Ludwigshafen DE
- 专利权人： BASF AKTIENGESELLSCHAFT
- 当前专利权人： BASF AKTIENGESELLSCHAFT
- 当前专利权人地址： 67056 Ludwigshafen DE
- 优先权： DE19632772 19960814
- 国际公布： WO9806740 19980219
- 主分类号： C07K5/02
- IPC分类号： C07K5/02 ; C07D207/22 ; C07D211/78 ; A61K38/05
摘要：
Disclosed are compounds having formula (I) wherein the radicals R, R?1, R2, R3, R4, R5 and R6¿, as well as l, m, and n have the meaning indicated in the description, and the production of said compounds. The new compounds can be used to combat illness. Also described are compounds having formula (II) wherein the radicals R, R?1, R2, R3, R4, R5 and R6¿, as well as l, m, and n have the meaning indicated in claim 1, and compounds having formula (III) wherein l and R have the meaning indicated in claim 1 and Y is an N protective group, or N-terminal protected or unprotected amino acid or represents H.
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