发明公开
EP0923602A1 IMMUNOCONTRACEPTIVE COMPOSITIONS CONTAINING SPERM ANTIGENS, AND METHODS OF USE
失效
哪些抗原抗精子的IMMUNKONTRAZEPTIVE组合物含有及使用方法
- 专利标题： IMMUNOCONTRACEPTIVE COMPOSITIONS CONTAINING SPERM ANTIGENS, AND METHODS OF USE
- 专利标题（中）： 哪些抗原抗精子的IMMUNKONTRAZEPTIVE组合物含有及使用方法
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申请号： EP97932497.0申请日： 1997-07-03
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公开(公告)号： EP0923602A1公开(公告)日： 1999-06-23
- 发明人: BLEIL, Jeffrey, D. , HEIN, Mich, B. , BOOKBINDER, Louis, H.
- 申请人： Zygam, Inc.
- 申请人地址： 1080 Joshua Way Vista, CA 92083 US
- 专利权人： Zygam, Inc.
- 当前专利权人： Zygam, Inc.
- 当前专利权人地址： 1080 Joshua Way Vista, CA 92083 US
- 代理机构： Baldock, Sharon Claire, et al
- 优先权： US19960674895 19960703
- 国际公布： WO1998000440 19980108
- 主分类号： G01N33
- IPC分类号： G01N33 ; A61K39 ; A61P15 ; C07K14 ; C07K16 ; C12N15 ; C12P21
摘要：
The invention relates generally to immunocontraceptive vaccine compositions comprising antigenic polypeptides having mammalian sp56 sperm protein antigenic determinants. The antigenic polypeptides can be synthetic polypeptides, fusion proteins and chimeric molecules. The vaccine is preferably administered to feral mammals in bait or feed formulations. Certain embodiments describe the use of species specific sequences of sp56. Also described are immunocontraceptive methods, antibodies immunoreactive with the sp56 antigenic determinants, and methods for screening for sperm fertility.
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