发明公开
- 专利标题： CYCLIC LIPOPEPTIDE ACYLASE
- 专利标题（中）： ZYCLISCHE LIPOPEPTID ACYLASE
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申请号： EP97926214申请日： 1997-06-11
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公开(公告)号： EP0933422A4公开(公告)日： 2005-02-02
- 发明人: UEDA SATOSHI , TANAKA MIHO , EZAKI MASAMI , SAKAMOTO KAZUTOSHI , HASHIMOTO SEIJI , OOHATA NOBUTAKA , TSUBOI MASARU , YAMASHITA MICHIO
- 申请人： FUJISAWA PHARMACEUTICAL CO
- 专利权人： FUJISAWA PHARMACEUTICAL CO
- 当前专利权人： FUJISAWA PHARMACEUTICAL CO
- 优先权： JP15194896 1996-06-13
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K7/56 ; C12N9/80 ; C07K5/12 ; C12N1/14 ; C12N9/14 ; C12P21/02
摘要：
A cyclic lipopeptide acylase which can effectively remove acyl side chains from cyclic lipopeptides, specifically substances FR901379 of general formula (I) and analogues thereof; and a process for the preparation of cyclic peptides by the use of this acylase, wherein R is acyl; R is hydroxyl or acyloxy; R is H or hydroxyl; R is H or hydroxyl; R is H or hydroxysulfonyloxy; and R is H or carbamoyl.
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IPC分类:
