发明公开
EP0942729A1 USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING STRESS DISORDERS
无效
NK-1受体拮抗剂的FOR应激障碍的治疗中的用途
- 专利标题： USE OF NK-1 RECEPTOR ANTAGONISTS FOR TREATING STRESS DISORDERS
- 专利标题（中）： NK-1受体拮抗剂的FOR应激障碍的治疗中的用途
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申请号： EP97952020.0申请日： 1997-11-25
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公开(公告)号： EP0942729A1公开(公告)日： 1999-09-22
- 发明人: BAKER, Raymond , CURTIS, Neil, Roy , ELLIOTT, Jason, Matthew , HARRISON, Timothy , HOLLINGWORTH, Gregory, John , JACKSON, Philip, Stephen , KULAGOWSKI, Janusz, Jozef , RUPNIAK, Nadia, Melanie , SEWARD, Eileen, Mary , SWAIN, Christopher, John , WILLIAMS, Brian, John
- 申请人： MERCK SHARP & DOHME LTD.
- 申请人地址： Hertford Road Hoddesdon Hertfordshire EN11 9BU GB
- 专利权人： MERCK SHARP & DOHME LTD.
- 当前专利权人： MERCK SHARP & DOHME LTD.
- 当前专利权人地址： Hertford Road Hoddesdon Hertfordshire EN11 9BU GB
- 代理机构： Hiscock, Ian James, et al
- 优先权： GB19960025051 19961202; GB19970001459 19970124; GB19970013715 19970627; GB19970016482 19970804; GB19970021171 19971007
- 国际公布： WO1998024440 19980611
- 主分类号： A61K31
- IPC分类号： A61K31 ; A61K45 ; A61P25 ; C07D211 ; C07D265 ; C07D413 ; C07D491
摘要：
The present invention provides the use of an orally active, long acting, CNS-penetrant NK-1 receptor antagonist for the manufacture of a medicament adapted for oral administration for the treatment or prevention of stress disorders without concomitant therapy with other anti-stress agents, methods of treatment using such a NK-1 receptor antagonist and pharmaceutical compositions comprising it.
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