发明公开
- 专利标题: GENE THERAPY FOR OBESITY
- 专利标题(中): 对肥胖基因治疗
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申请号: EP97931187.0申请日: 1997-06-20
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公开(公告)号: EP0954579A1公开(公告)日: 1999-11-10
- 发明人: MORSY, Manal, A. , GU, Ming, Cheng , ZHAO, Jing , CASKEY, C., Thomas , KOCHANET, Stefan
- 申请人: MERCK & CO., INC. , BAYLOR COLLEGE OF MEDICINE
- 申请人地址: 126 East Lincoln Avenue Rahway, New Jersey 07065 US
- 专利权人: MERCK & CO., INC.,BAYLOR COLLEGE OF MEDICINE
- 当前专利权人: MERCK & CO., INC.,BAYLOR COLLEGE OF MEDICINE
- 当前专利权人地址: 126 East Lincoln Avenue Rahway, New Jersey 07065 US
- 代理机构: Horgan, James Michael Frederic
- 优先权: US19960020813P 19960620; GB19960015788 19960726; US19960207535P 19960926
- 国际公布: WO1997048806 19971224
- 主分类号: C12N15
- IPC分类号: C12N15 ; A61K48 ; C07K14 ; C12N5
摘要:
Gene therapy can treat obesity in mammals. An obesity regulating gene is delivered to a mammal. Preferably, the gene encodes letpin or a leptin receptor. The protein which is delivered and expressed in vivo is more effective than protein which is injected into the animal.
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