A substantially pure, isolated, antigenic protein from fungi of the genus
Malassezia , characterized in that said antigenic protein has a binding ability to IgE antibodies from patients with allergoses; an antigenic fragment derived from the antigenic protein; and an antibody against the antigenic protein or fragments thereof. According to the present invention, there can be provided an isolated and purified antigenic protein having high purity from
Malassezia , antigenic fragments thereof, and a specific antibody against those antigenic protein or fragments thereof. In addition, there can be provided a diagnostic agent, a therapeutic agent, or a prophylactic drug for
Malassezia allergoses, wherein the agent includes, as an active ingredient, the antigenic protein or fragments thereof.