公开(公告)号：EP0955366A1

公开(公告)日：1999-11-10

申请号：EP96941211.3

申请日：1996-12-10

申请人： TAKARA SHUZO CO. LTD.

发明人： TAKESAKO, Kazutoh ,  OKADO, Takashi ,  YAGIHARA, Tomoko ,  KURODA, Masanobu ,  ONISHI, Yoshimi ,  KATO, Ikunoshin ,  AKIYAMA, Kazuo ,  YASUEDA, Hiroshi ,  YAMAGUCHI, Hideyo

IPC分类号： C12N15/31 ,  C07K14/37 ,  C07K16/14 ,  C12P21/08 ,  C12Q1/68 ,  G01N33/53 ,  A61K39/00

CPC分类号： A61K39/0002 ,  A61K38/00 ,  A61K39/00 ,  C07K14/37 ,  C07K16/14 ,  Y10S530/858

摘要： A substantially pure, isolated, antigenic protein from fungi of the genus
Malassezia , characterized in that said antigenic protein has a binding ability to IgE antibodies from patients with allergoses; an antigenic fragment derived from the antigenic protein; and an antibody against the antigenic protein or fragments thereof. According to the present invention, there can be provided an isolated and purified antigenic protein having high purity from
Malassezia , antigenic fragments thereof, and a specific antibody against those antigenic protein or fragments thereof. In addition, there can be provided a diagnostic agent, a therapeutic agent, or a prophylactic drug for
Malassezia allergoses, wherein the agent includes, as an active ingredient, the antigenic protein or fragments thereof.