发明公开
EP0970232A2 NON-IMMUNOGENIC PRODRUGS AND SELECTABLE MARKERS FOR USE IN GENE THERAPY
失效
非免疫原性PRE药品和选择标记用于基因治疗
- 专利标题： NON-IMMUNOGENIC PRODRUGS AND SELECTABLE MARKERS FOR USE IN GENE THERAPY
- 专利标题（中）： 非免疫原性PRE药品和选择标记用于基因治疗
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申请号： EP98902548.1申请日： 1998-01-14
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公开(公告)号： EP0970232A2公开(公告)日： 2000-01-12
- 发明人: Jolly, Douglas J. , Moore, Margaret Dow , Chada, Sunil
- 申请人： Chiron Corporation
- 申请人地址： 4560 Horton Street,R440 Emeryville,California 94608 US
- 专利权人： Chiron Corporation
- 当前专利权人： Chiron Corporation
- 当前专利权人地址： 4560 Horton Street,R440 Emeryville,California 94608 US
- 代理机构： Irvine, Jonquil Claire
- 优先权： US35473P 19970114; US38339P 19970227; US6298 19980113
- 国际公布： WO9830709 19980716
- 主分类号： C12N15/86
- IPC分类号： C12N15/86 ; C12N15/12 ; C12Q1/68 ; A61K48/00 ; C07K14/755
摘要：
The present invention provides methods for delivering a gene delivery vehicle to a warm-blooded animal, comprising the step of administering to a warm-blooded animal a gene delivery vehicle which directs the expression of a non-immunogenic selectable marker. Within other aspects, methods are provided for delivering a gene delivery vehicle to a warm-blooded animal, comprising the step of administering to a warm-blooded animal a gene delivery vehicle which directs the expression of a non-immunogenic molecule which is capable of activating an otherwise inactive compound into an active compound.
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