发明公开
- 专利标题： Compounds having selectivity for retinoid x receptors
- 专利标题（中）： 对类视黄醇x受体具有选择性的化合物
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申请号： EP99118828.5申请日： 1993-04-22
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公开(公告)号： EP0983992A3公开(公告)日： 2000-11-29
- 发明人: Boehm, Marcus F. , Heyman, Richard A. , Zhi, Lin
- 申请人： LIGAND PHARMACEUTICALS, INC.
- 申请人地址： 9393 Towne Centre Drive, Suite 100 San Diego, CA 92121 US
- 专利权人： LIGAND PHARMACEUTICALS, INC.
- 当前专利权人： LIGAND PHARMACEUTICALS, INC.
- 当前专利权人地址： 9393 Towne Centre Drive, Suite 100 San Diego, CA 92121 US
- 代理机构： Goldin, Douglas Michael
- 优先权： US872707 19920422; US944783 19920911; US3223 19930111; US27747 19930305; US52051 19930421
- 主分类号： C07C63/49
- IPC分类号： C07C63/49 ; A61K31/19 ; A61K31/44 ; C07C63/72 ; C07C65/40 ; C07C69/76 ; C07C235/84 ; C07D307/68 ; C07D333/38 ; C07D213/80 ; C07D311/58 ; C07D213/79 ; C07D207/40
摘要：
Compounds, compositions, and method for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass of Retinoic Acid Receptors (RARs). Examples of such compounds are bicyclic benzyl, pyridinyl, thiophene, furanyl, and pyrrole derivatives. The disclosed methods employ compounds for modulating processes selectively mediated by Retinoid X Receptors.
公开/授权文献
- EP0983992B1 Compounds having selectivity for retinoid x receptors 公开/授权日：2005-10-26
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