发明授权
- 专利标题： PIPERAZINE DERIVATIVES ACTIVE ON THE LOWER URINARY TRACT
- 专利标题（中）： 哌嗪下尿路的治疗
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申请号： EP98943811.4申请日： 1998-07-31
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公开(公告)号： EP1000046B1公开(公告)日： 2003-11-26
- 发明人: LEONARDI, Amedeo , MOTTA, Gianni , RIVA, Carlo , TESTA, Rodolfo
- 申请人： RECORDATI S.A. , RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a.
- 申请人地址： Piazza Boffalora 4 6830 Chiasso CH
- 专利权人： RECORDATI S.A.,RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a.
- 当前专利权人： RECORDATI S.A.,RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a.
- 当前专利权人地址： Piazza Boffalora 4 6830 Chiasso CH
- 代理机构： McKelvey, Ian Edward
- 优先权： ITMI971861 19970801
- 国际公布： WO99006383 19990211
- 主分类号： C07D295/12
- IPC分类号： C07D295/12 ; A61K31/495
摘要：
Piperazine derivatives of formula (I) (Ar, Ar' and B are substituted or unsubstituted aryl or heteroaryl groups, Y = N, CH, C-OH, C-CN or C-CONH2, R = H or lower alkyl, Z = CH2 or CH2CH2, Z' = bond or CH2 or CH2CH2) bind to 5HT1A receptors and are useful for the treatment of neuromuscular dysfunctions of the lower urinary tract. The use of these compounds for the preparation of a medicament for this treatment is claimed, and some of the compounds (Z = CH2, Z' = bond) are claimed per se.
公开/授权文献
- EP1000046A1 PIPERAZINE DERIVATIVES ACTIVE ON THE LOWER URINARY TRACT 公开/授权日：2000-05-17
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