发明公开
EP1001032A3 Recombinant retroviruses delivering vector constructs to target cells
失效
提供重组逆转录病毒载体的结构，以对靶细胞的
- 专利标题： Recombinant retroviruses delivering vector constructs to target cells
- 专利标题（中）： 提供重组逆转录病毒载体的结构，以对靶细胞的
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申请号： EP99121015.4申请日： 1990-08-17
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公开(公告)号： EP1001032A3公开(公告)日： 2005-02-23
- 发明人: Gruber, Harry, E. , Jolly, Douglas J. , Respess, James G. , Laikind, Paul K. , Chang, Stephen M. , Chada, Sunil D. , Warner, John F. , Barber, Jack R. , St. Louis, Daniel C.
- 申请人： CHIRON CORPORATION
- 申请人地址： 4560 Horton Street Emeryville California 94608-2916 US
- 专利权人： CHIRON CORPORATION
- 当前专利权人： CHIRON CORPORATION
- 当前专利权人地址： 4560 Horton Street Emeryville California 94608-2916 US
- 代理机构： Hallybone, Huw George
- 优先权： US395932 19890818; US565606 19900810
- 主分类号： C12N15/867
- IPC分类号： C12N15/867 ; A61K48/00
摘要：
The present invention relates to replication-defective recombinant retrovirus capable of infecting human cells and carrying a vector construct which is capable of directing the expression of both: a. an MHC protein or modified form thereof and b. an antigen which is not an MHC protein or modified form thereof, said MHC protein or modified form thereof in cells infected with said retrovirus within a human or animal body being capable of presenting said antigen or a portion thereof so as to stimulate a cell-mediated immune response.
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