发明授权
- 专利标题： SPHINGOSINE ANALOGUES
- 专利标题（中）： 类神经类似物
-
申请号： EP98907195.6申请日： 1998-03-12
-
公开(公告)号： EP1002790B1公开(公告)日： 2005-12-28
- 发明人: TAKESAKO, Kazutoh , KUROME, Toru , AWAZU, Naoyuki , KATO, Ikunoshin
- 申请人： TAKARA BIO INC.
- 申请人地址： 4-1, Seta 3-chome Otsu-shi, Shiga 520-2193 JP
- 专利权人： TAKARA BIO INC.
- 当前专利权人： TAKARA BIO INC.
- 当前专利权人地址： 4-1, Seta 3-chome Otsu-shi, Shiga 520-2193 JP
- 代理机构： Hubert, Philippe
- 优先权： JP7909497 19970312; JP26796997 19970911
- 国际公布： WO1998040349 19980917
- 主分类号： C07C215/10
- IPC分类号： C07C215/10 ; C07C229/22 ; C07C271/22 ; C07C215/24 ; C07C229/30 ; C07D263/06
摘要：
Novel sphingosine analogues useful as intermediates for the synthesis of novel lipid derivatives such as sphingolipid derivatives controlling the function of sphingolipid. The sphingosine analogues are represented by general formula (I), wherein Q?1 and Q2¿ are each independently hydrogen, C¿1?-C4 alkyl, C2-C5 acyl or an amino-protecting group and Q?3¿ is hydrogen or a hydroxyl-protecting group, or alternatively Q?2 and Q3¿ are united to form isopropylidene and Q1 is hydrogen or an amino-protecting group; Q?4 and Q5¿ are each independently hydroxyl, C¿2?-C5 acyl, -O-Q?6¿ or hydrogen, or alternatively Q?4 and Q5¿ may be united to form a covalent bond; Q6 is a hydroxyl-protecting group; X1 is -COOH, -CONH¿2?, -CO-Q?7, -CH¿2OH or -CH2O-Q8; Q7 is a carboxyl-protecting group; and Q8 is a hydroxyl-protecting group.
公开/授权文献
- EP1002790A1 SPHINGOSINE ANALOGUES 公开/授权日：2000-05-24
信息查询
