发明公开
- 专利标题： MAGE-3 PEPTIDES PRESENTED BY HLA CLASS II MOLECULES
- 专利标题（中）： MAGE-3肽由HLA II类分子呈现BE
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申请号： EP98945923.5申请日： 1998-09-04
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公开(公告)号： EP1012283A1公开(公告)日： 2000-06-28
- 发明人: THIELEMANS, Kris , HEIRMAN, Carlo , CORTHALS, Jurgen , CHAUX, Pascal , STROOBANT, Vincent , BOON-FALLEUR, Thierry , VAN DER BRUGGEN, Pierre , LUITEN, Rosalie
- 申请人： LUDWIG INSTITUTE FOR CANCER RESEARCH , VRIJE UNIVERSITEIT BRUSSEL
- 申请人地址： 605 Third Avenue New York,New York 10158 US
- 专利权人： LUDWIG INSTITUTE FOR CANCER RESEARCH,VRIJE UNIVERSITEIT BRUSSEL
- 当前专利权人： LUDWIG INSTITUTE FOR CANCER RESEARCH,VRIJE UNIVERSITEIT BRUSSEL
- 当前专利权人地址： 605 Third Avenue New York,New York 10158 US
- 代理机构： Baldock, Sharon Claire
- 优先权： US928615 19970912
- 国际公布： WO9914326 19990325
- 主分类号： C12N15/12
- IPC分类号： C12N15/12 ; C07K14/705 ; C07K19/00 ; G01N33/53 ; G01N33/68 ; A61K38/17 ; A61K35/26 ; C07K16/30 ; C12N5/08
摘要：
The invention describes HLA class II binding peptides encoded by the MAGE-3 tumor associated gene, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides stimulate the activity and proliferation of CD4+T lymphocytes. Methods and products are also provided for diagnosing and treating conditions characterized by expression of the MAGE-3 gene.
公开/授权文献
- EP1012283B1 MAGE-3 PEPTIDES PRESENTED BY HLA CLASS II MOLECULES 公开/授权日：2009-06-03
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