发明公开
- 专利标题： NOVEL PYRIMIDINE DERIVATIVE
- 专利标题（中）： PYRIMIDINDERIVAT
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申请号： EP98907199.8申请日： 1998-03-12
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公开(公告)号： EP1019501A1公开(公告)日： 2000-07-19
- 发明人: YAMADA, Satoshi , KINOSHITA, Naosumi , YASUMURA, Koichi , EDAMATSU, Koji , NAGAHAMA, Takao , ISHIKAWA, Shintaro , YAMAUCHI, Takeshi , KISHI, Kazumasa , SUGIYAMA, Kazuhisa
- 申请人： OTSUKA PHARMACEUTICAL CO., LTD.
- 申请人地址： 9, Kandatsukasa-cho 2-chome Chiyoda-ku,Tokyo 101-0048 JP
- 专利权人： OTSUKA PHARMACEUTICAL CO., LTD.
- 当前专利权人： OTSUKA PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： 9, Kandatsukasa-cho 2-chome Chiyoda-ku,Tokyo 101-0048 JP
- 代理机构： Ruffles, Graham Keith
- 优先权： JP6155097 19970314
- 国际公布： WO9841526 19980924
- 主分类号： C12N15/12
- IPC分类号： C12N15/12
摘要：
The present invention provides a novel pyrimidine derivative represented by general formula (1), wherein R, R?4 and R8¿ are the same as defined in the specification, or pharmaceutically acceptable salt thereof, which possesses an excellent activity for inhibiting the formation of NO (nitrogen oxide) in vivo.
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