发明公开
EP1037878A2 METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES
审中-公开
为中央神经系统疾病的治疗代谢型谷氨酸受体拮抗剂
- 专利标题： METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES
- 专利标题（中）： 为中央神经系统疾病的治疗代谢型谷氨酸受体拮抗剂
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申请号： EP98959535.0申请日： 1998-11-20
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公开(公告)号： EP1037878A2公开(公告)日： 2000-09-27
- 发明人: VAN WAGENEN, Bradford, C. , MOE, Scott, T. , SMITH, Daryl, L. , SHEEHAN, Susan, M. , SHCHERBAKOVA, Irina , TRAVATO, Richard , WALTON, Ruth , BARMORE, Robert , DELMAR, Eric, G. , STORMANN, Thomas, M.
- 申请人： NPS PHARMACEUTICALS, INC.
- 申请人地址： 420 Chipeta Way Salt Lake CityUtah 84108 US
- 专利权人： NPS PHARMACEUTICALS, INC.
- 当前专利权人： NPS PHARMACEUTICALS, INC.
- 当前专利权人地址： 420 Chipeta Way Salt Lake CityUtah 84108 US
- 代理机构： Frohwitter, Bernhard, Dipl.-Ing.
- 优先权： US66758P 19971121
- 国际公布： WO9926927 19990603
- 主分类号： C07D215/38
- IPC分类号： C07D215/38 ; C07D241/44 ; C07D277/72 ; A61K31/47 ; A61K31/495 ; A61K31/425
摘要：
The present invention provides compounds, and pharmaceutical compositions containing those compounds, that act as antagonists at metabotropic glutamate receptors. The compounds are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.
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