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1.发明公开METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES 审中-公开为中央神经系统疾病的治疗代谢型谷氨酸受体拮抗剂
公开(公告)号：EP1037878A2
公开(公告)日：2000-09-27
申请号：EP98959535.0
申请日：1998-11-20
发明人： VAN WAGENEN, Bradford, C. , MOE, Scott, T. , SMITH, Daryl, L. , SHEEHAN, Susan, M. , SHCHERBAKOVA, Irina , TRAVATO, Richard , WALTON, Ruth , BARMORE, Robert , DELMAR, Eric, G. , STORMANN, Thomas, M.
IPC分类号： C07D215/38 , C07D241/44 , C07D277/72 , A61K31/47 , A61K31/495 , A61K31/425
CPC分类号： C07D213/81 , C07D213/82 , C07D215/12 , C07D215/20 , C07D215/38 , C07D215/48 , C07D215/54 , C07D217/26 , C07D231/12 , C07D233/56 , C07D241/42 , C07D241/44 , C07D249/08 , C07D277/68 , C07D277/70 , C07D491/04
摘要： The present invention provides compounds, and pharmaceutical compositions containing those compounds, that act as antagonists at metabotropic glutamate receptors. The compounds are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.
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2.发明授权METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS AND THEIR USE FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES 有权代谢型谷氨酸受体拮抗剂及其治疗中枢神经系统疾病的应用
公开(公告)号：EP1196397B1
公开(公告)日：2005-08-17
申请号：EP00936465.4
申请日：2000-06-02
发明人： VAN WAGENEN, Bradford, C. , MOE, Scott, T. , SMITH, Daryl, L. , SHEEHAN, Susan, M. , SHCHERBAKOVA, Irina , TRAVATO, Richard , WALTON, Ruth , BARMORE, Robert , DELMAR, Eric, G. , STORMANN, Thomas, M.
IPC分类号： C07D241/44 , C07D215/54 , C07D209/42 , C07D213/82 , C07D307/68 , C07D307/84 , C07D333/38 , C07D333/68 , A61K31/495 , A61K31/404 , A61P25/00
CPC分类号： C07D213/81 , A61K31/404 , A61K31/495 , C07D209/42 , C07D213/82 , C07D215/12 , C07D215/20 , C07D215/38 , C07D215/48 , C07D215/50 , C07D215/54 , C07D217/26 , C07D231/12 , C07D233/56 , C07D241/42 , C07D241/44 , C07D249/08 , C07D277/68 , C07D277/70 , C07D307/68 , C07D307/84 , C07D333/38 , C07D333/68 , C07D401/04 , C07D401/12 , C07D491/04
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3.发明公开METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS AND THEIR USE FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES 有权为中央神经系统疾病的治疗代谢型谷氨酸受体拮抗剂
公开(公告)号：EP1196397A1
公开(公告)日：2002-04-17
申请号：EP00936465.4
申请日：2000-06-02
发明人： VAN WAGENEN, Bradford, C. , MOE, Scott, T. , SMITH, Daryl, L. , SHEEHAN, Susan, M. , SHCHERBAKOVA, Irina , TRAVATO, Richard , WALTON, Ruth , BARMORE, Robert , DELMAR, Eric, G. , STORMANN, Thomas, M.
IPC分类号： C07D241/44 , C07D215/54 , C07D209/42 , C07D213/82 , C07D307/68 , C07D307/84 , C07D333/38 , C07D333/68 , A61K31/495 , A61K31/404 , A61P25/00
CPC分类号： C07D213/81 , A61K31/404 , A61K31/495 , C07D209/42 , C07D213/82 , C07D215/12 , C07D215/20 , C07D215/38 , C07D215/48 , C07D215/50 , C07D215/54 , C07D217/26 , C07D231/12 , C07D233/56 , C07D241/42 , C07D241/44 , C07D249/08 , C07D277/68 , C07D277/70 , C07D307/68 , C07D307/84 , C07D333/38 , C07D333/68 , C07D401/04 , C07D401/12 , C07D491/04
摘要： The present invention provides compounds, and pharmaceutical compositions containing those compounds, that are active at metabotropic glutamate receptors. The compounds are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.
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