Novel phenylaminoalkylcarboxylic acid derivatives represented by general formula (I) and pharmacologically acceptable salts thereof, which have an excellent effect of stimulating β3-adrenergic receptor and are useful as preventives or remedies for obesity, hyperglycemia, diseases caused by accelerated intestinal motion, frequent urination or urinary incontinence, depression, cholelithiasis, diseases caused by accelerated biliary motion, etc. In said formula, R1 represents hydroxy, lower alkyl, aralkoxy, amino, alicyclic amino optionally substituted by hydroxy or lower alkyl, or mono- or di(lower alkyl)amino; R2 represents hydroxy or lower alkyl; R3 represents hydrogen or halogeno; R?4 and R5¿ represent each hydrogen, halogeno or lower alkyl; A represents lower alkylene; the carbon atom bearing the mark (R) is a carbon atom with the (R) configuration; and the carbon atom bearing the mark (S) is one with the (S) configuration.