发明公开
- 专利标题： INDUCTION OF APOPTIC OR CYTOTOXIC GENE EXPRESSION BY ADENOVIRAL MEDIATED GENE CODELIVERY
- 专利标题（中）： 腺病毒诱导的凋亡基因表达
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申请号： EP99913854.8申请日： 1999-03-11
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公开(公告)号： EP1070122A2公开(公告)日： 2001-01-24
- 发明人: MCDONNELL, Timothy, J. , SWISHER, Stephen, G. , FANG, Bingliang , BRUCKHEIMER, Elizabeth, M. , SARKISS, Mona, G. , JI, Li , ROTH, Jack, A.
- 申请人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- 申请人地址： Office of General Council,201 West 7th Street Austin,Texas 78701 US
- 专利权人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- 当前专利权人： BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- 当前专利权人地址： Office of General Council,201 West 7th Street Austin,Texas 78701 US
- 代理机构： Gowshall, Jonathan Vallance
- 优先权： US77541P 19980311
- 国际公布： WO9946371 19990916
- 主分类号： C12N15/00
- IPC分类号： C12N15/00 ; A01N43/04
摘要：
The present invention generally relates to viral vectors and their use as expression vectors for transforming human cells, both in vitro and in vivo. More particularly, the present invention relates to adenoviral vectors containing propapoptotic genes and their use in cancer therapy.
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