公开(公告)号：EP3697889A1

公开(公告)日：2020-08-26

申请号：EP18868400.5

申请日：2018-10-19

申请人： University of Pittsburgh - of The Commonwealth System of Higher Education ,  Fondazione Ri.MED

发明人： MARINO, Davide ,  GOTTARDI, Riccardo ,  TUAN, Rocky Sung Chi

IPC分类号： C12M1/00 ,  C12M1/02 ,  C12M3/00 ,  B01L3/02 ,  G01F11/02

公开(公告)号：EP3179393B1

公开(公告)日：2020-07-08

申请号：EP16191856.0

申请日：2013-01-28

申请人： Genomic Health, Inc.

发明人： SHAK, Steve ,  LEE, Mark ,  NOVOTNY, William ,  MADDALA, Tara ,  CRAGER, Michael ,  CHERBAVAZ, Diana ,  PELHAM, Robert ,  MILLWARD, Carl L. ,  KNEZEVIC, Dejan

IPC分类号： C12Q1/68 ,  G16B25/10

公开(公告)号：EP3434201B1

公开(公告)日：2020-06-24

申请号：EP18195811.7

申请日：2011-02-17

申请人： LifeCell Corporation

发明人： STEVENSON, Eric ,  SUN, Wendell ,  BARERE, Aaron

IPC分类号： A61B17/08 ,  A61F13/00

公开(公告)号：EP3655031A1

公开(公告)日：2020-05-27

申请号：EP18752341.0

申请日：2018-07-20

申请人： The U.S.A. as represented by the Secretary, Department of Health and Human Services

发明人： BASH, Margaret ,  MATTHIAS, Kathryn

IPC分类号： A61K39/095 ,  A61P31/04

公开(公告)号：EP3270965B1

公开(公告)日：2020-05-06

申请号：EP16765773.3

申请日：2016-03-17

申请人： Seattle Genetics, Inc.

发明人： LEWIS, Timothy ,  GORDON, Kristine ,  WESTENDORF, Lori

IPC分类号： A61K39/395 ,  C07K16/18 ,  C07K16/28 ,  C07K5/02 ,  A61K47/68 ,  A61P35/00

公开(公告)号：EP3622974A1

公开(公告)日：2020-03-18

申请号：EP19204646.4

申请日：2012-11-08

申请人： LifeCell Corporation

发明人： OWENS, Rick ,  XU, Hui ,  SUN, Wenquan

IPC分类号： A61L31/00

摘要： Acellular tissue matrix compositions for use in tissue approximation are provided. Also provided are methods for making and using the compositions to approximate tissue.

公开(公告)号：EP3622821A1

公开(公告)日：2020-03-18

申请号：EP19202040.2

申请日：2014-05-15

申请人： Regents of the University of Minnesota ,  REGENXBIO Inc.

发明人： MCIVOR, R., Scott ,  BELUR, Lalitha R. ,  LOW, Walter ,  FAIRBANKS, Carolyn ,  KOZARSKY, Karen

IPC分类号： A01N63/00 ,  C12N15/00 ,  C12N15/86

摘要： A method to prevent, inhibit or treat one or more symptoms associated with a disease of the central nervous system by intrathecally, intracerebroventricularly or endovascularly administering a rAAV encoding a gene product associated with the disease, e.g., a mammal in which the gene product is absent or present at a reduced level relative to a mammal without the disease.

公开(公告)号：EP3066118B1

公开(公告)日：2020-01-08

申请号：EP14805427.3

申请日：2014-11-06

申请人： The U.S.A. as represented by the Secretary, Department of Health and Human Services

发明人： ORENTAS, Rimas ,  MACKALL, Crystal

IPC分类号： C07K14/725 ,  C07K16/30 ,  C07K16/46

公开(公告)号：EP3583201A1

公开(公告)日：2019-12-25

申请号：EP18754542.1

申请日：2018-02-13

申请人： University of Pittsburgh - Of the Commonwealth System of Higher Education

发明人： SOTO-GUTIERREZ, Alejandro ,  MASHIMO, Tomoji ,  COLLIN DE I'HORTET, Alexandra, Sylvie ,  ALVAREZ, Eduardo, Cervantes ,  LEPE, Jorge, Guzman ,  HANDA, Kan ,  TAKEISHI, Kazuki ,  WANG, Yang ,  POPOVIC, Branimir

IPC分类号： C12N5/074 ,  A61K35/407 ,  A01K67/027

公开(公告)号：EP3581214A1

公开(公告)日：2019-12-18

申请号：EP19187888.3

申请日：2009-06-04

申请人： LifeCell Corporation

发明人： Sun, Wendell

IPC分类号： A61L27/36 ,  F01C21/06 ,  F03C2/08

摘要： A method of producing a modified acellular tissue matrix (mATM) from an acellular tissue matrix (ATM), where the mATM has a reduced stretchiness relative to the ATM, without substantially compromising its associated structural or functional integrity. The method includes providing an acellular tissue matrix (ATM) and exposing the ATM to elastase for a period of time.