发明公开
EP1084105A1 CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT
审中-公开
抗菌药物CARBOPENEMVERBINDUNGEN,与你和组合物的方法
- 专利标题: CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT
- 专利标题(中): 抗菌药物CARBOPENEMVERBINDUNGEN,与你和组合物的方法
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申请号: EP99924539.2申请日: 1999-05-28
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公开(公告)号: EP1084105A1公开(公告)日: 2001-03-21
- 发明人: DININNO, Frank, P. , DYKSTRA, Kevin, D.
- 申请人: MERCK & CO., INC.
- 申请人地址: 126 East Lincoln Avenue Rahway, New Jersey 07065 US
- 专利权人: MERCK & CO., INC.
- 当前专利权人: MERCK & CO., INC.
- 当前专利权人地址: 126 East Lincoln Avenue Rahway, New Jersey 07065 US
- 代理机构: Hiscock, Ian James
- 优先权: US87722P 19980602
- 国际公布: WO9962878 19991209
- 主分类号: C07D205/00
- IPC分类号: C07D205/00 ; A61K31/395
摘要:
The present invention relates to tricyclic carbapenem antibacterial agents in which the carbapenem nucleus is fused to a 6-membered carbocyclic ring. The compound is further substituted with various substituent groups including at least one cationic group. The compounds are represented by formula (I). Pharmaceutical compositions and methods of use are also included.
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