发明公开
- 专利标题: CLONING AND IDENTIFICATION OF THE MOTILIN RECEPTOR
- 专利标题(中): 克隆和胃动素受体鉴定
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申请号: EP99928453.2申请日: 1999-06-08
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公开(公告)号: EP1086117A1公开(公告)日: 2001-03-28
- 发明人: FEIGHNER, Scott, D. , PATCHETT, Arthur, A. , TAN, Carina , MCKEE, Karen , MACNEIL, Douglas , HOWARD, Andrew, D. , PONG, Sheng-Shung , SMITH, Roy, G.
- 申请人: MERCK & CO., INC.
- 申请人地址: 126 East Lincoln Avenue Rahway, New Jersey 07065 US
- 专利权人: MERCK & CO., INC.
- 当前专利权人: MERCK & CO., INC.
- 当前专利权人地址: 126 East Lincoln Avenue Rahway, New Jersey 07065 US
- 代理机构: Horgan, James Michael Frederic
- 优先权: US89098P 19980612
- 国际公布: WO9964436 19991216
- 主分类号: C07H21/04
- IPC分类号: C07H21/04 ; C07K14/705 ; C12N15/09 ; C12N15/63 ; C12Q1/68
摘要:
The motilin receptor has been isolated and cloned, and nucleic acid sequences are given. Two splice variants have been identified. Also, assays for motilin receptor ligands are given. The identification of the cloned motilin receptor may be used to screen and identify compounds which bind to the receptor for use in a variety of gastric conditions, including gastric motility disorders.
公开/授权文献
- EP1086117B1 CLONING AND IDENTIFICATION OF THE MOTILIN RECEPTOR 公开/授权日:2007-02-21
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