发明公开
EP1087015A3 Cloning and uses of a novel nucleotide sequence coding for glucose-6-phosphate isomerase (gpi) from bacteria
有权
使用新的葡萄糖-6-磷酸异构酶基因的克隆和核苷酸序列包含(GPI),该细菌
- 专利标题: Cloning and uses of a novel nucleotide sequence coding for glucose-6-phosphate isomerase (gpi) from bacteria
- 专利标题(中): 使用新的葡萄糖-6-磷酸异构酶基因的克隆和核苷酸序列包含(GPI),该细菌
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申请号: EP00118052.0申请日: 2000-08-23
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公开(公告)号: EP1087015A3公开(公告)日: 2003-07-09
- 发明人: Dunican, L. K., Prof. , McCormback, Ashling , Stapelton, Cliona , Burke, Kevin , O'Donohue, Michael , Marx, Achim, Dr. , Möckel, Bettina, Dr.
- 申请人: Degussa AG , National University of Ireland
- 申请人地址: Bennigsenplatz 1 40474 Düsseldorf DE
- 专利权人: Degussa AG,National University of Ireland
- 当前专利权人: Degussa AG,National University of Ireland
- 当前专利权人地址: Bennigsenplatz 1 40474 Düsseldorf DE
- 优先权: US396478 19990915
- 主分类号: C12N15/61
- IPC分类号: C12N15/61 ; C12N15/70 ; C12N9/90 ; C12N9/10 ; C12N9/12 ; C12N1/21 ; C12P13/08 ; C12P13/22
摘要:
Isolated polynucleotide containing a polynucleotide sequence selected from the group a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2, b) polynucleotide which codes for a polypeptide which contains an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 successive bases of the polynucleotide sequence of a), b) or c), and process for increasing metabolic flux through the pentose phosphate cycle by attenuating the pgi gene.
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