发明公开
EP1093818A1 POWDERY PREPARATION FOR MUCOSAL ADMINISTRATION CONTAINING POLYMERIC MEDICINE
有权
粉状研制应用粘膜其中一种聚合物药物CONTAINS
- 专利标题: POWDERY PREPARATION FOR MUCOSAL ADMINISTRATION CONTAINING POLYMERIC MEDICINE
- 专利标题(中): 粉状研制应用粘膜其中一种聚合物药物CONTAINS
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申请号: EP99926887.3申请日: 1999-07-01
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公开(公告)号: EP1093818A1公开(公告)日: 2001-04-25
- 发明人: NOMURA, Hideaki Iyaku Kaihatsu Kenkyusho , UEKI, Yosuke Iyaku Kaihatsu Kenkyusho
- 申请人: Kirin-Amgen Inc.
- 申请人地址: 1209 Orange Street Wilmington, DE 19801 US
- 专利权人: Kirin-Amgen Inc.
- 当前专利权人: Kirin-Amgen Inc.
- 当前专利权人地址: 1209 Orange Street Wilmington, DE 19801 US
- 代理机构: HOFFMANN - EITLE
- 优先权: JP19272298 19980708; JP8154999 19990325
- 国际公布: WO0002574 20000120
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K38/18 ; A61K38/27 ; A61K38/28 ; A61K39/145 ; A61K39/395 ; A61K9/14 ; A61K47/30 ; A61K47/42
摘要:
A preparation in powder form for administration through mucosa, comprising a medicine of high molecular weight and a cationic polymer is disclosed.
By adding a cationic polymer (in particular, a copolymer of aminoalkylmethacrylate or polyvinyl acetal diethylaminoacetate) or a cationic polymer plus a viscous polymer to a medicine of high molecular weight for producing a preparation in powder form, it is possible to achieve effective absorption of the medicine of high molecular weight through mucosa.
By adding a cationic polymer (in particular, a copolymer of aminoalkylmethacrylate or polyvinyl acetal diethylaminoacetate) or a cationic polymer plus a viscous polymer to a medicine of high molecular weight for producing a preparation in powder form, it is possible to achieve effective absorption of the medicine of high molecular weight through mucosa.
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