发明公开
EP1109799A1 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS
有权
4,5-DIARYL-3（2H） - 呋喃酮衍生物CYPOOXYGENASE-2 INHIBITOREN
- 专利标题： 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS
- 专利标题（中）： 4,5-DIARYL-3（2H） - 呋喃酮衍生物CYPOOXYGENASE-2 INHIBITOREN
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申请号： EP00921133.5申请日： 2000-04-12
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公开(公告)号： EP1109799A1公开(公告)日： 2001-06-27
- 发明人: SHIN, Song, Seok , NOH, Min-Soo , BYUN, Young Joo , CHOI, Jin Kyu , KIM, Jin Kwan , LIM, Kyung Min , KIM, Ji Young , CHOI, Young Hoon , HA, Jun-Yong , LEE, Ki-Wha , MOH, Joo Hyun , JEONG, Yeon Su , CHUNG, Shin , JOO, Yung Hyup , LEE, Chang Hoon , KANG, Seon Hwa , PARK, Young-Ho , YI, Jung Bum
- 申请人： PACIFIC CORPORATION
- 申请人地址： 181, Hankang-ro 2-kaYongsan-ku Seoul 140-777 KR
- 专利权人： PACIFIC CORPORATION
- 当前专利权人： PACIFIC CORPORATION
- 当前专利权人地址： 181, Hankang-ro 2-kaYongsan-ku Seoul 140-777 KR
- 代理机构： Harrison, Ivor Stanley
- 优先权： KR9913170 19990414; KR9929779 19990722; KR9939043 19990913; KR0016866 20000331; KR0017647 20000404
- 国际公布： WO0061571 20001019
- 主分类号： C07D307/32
- IPC分类号： C07D307/32 ; A61K31/341
摘要：
The present invention provides a novel class of 4,5-diaryl-3(2H)-furanone derivatives, which inhibit strongly and selectively COX-2 over COX-1. They are useful to treat inflammation, inflammation-associated disorders, and COX-2 mediated diseases.
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