发明公开
- 专利标题： BICYCLIC HETEROCYCLES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, AND PROCESSES FOR PREPARING THEM
- 专利标题（中）： 双环杂环，含有它们的组合物，和方法及其
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申请号： EP00909360.0申请日： 2000-03-14
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公开(公告)号： EP1163227A1公开(公告)日： 2001-12-19
- 发明人: HIMMELSBACH, Frank , LANGKOPF, Elke , BLECH, Stefan , JUNG, Birgit , METZ, Thomas , SOLCA, Flavio
- 申请人： Boehringer Ingelheim Pharma KG
- 申请人地址： 55216 Ingelheim am Rhein DE
- 专利权人： Boehringer Ingelheim Pharma KG
- 当前专利权人： Boehringer Ingelheim Pharma KG
- 当前专利权人地址： 55216 Ingelheim am Rhein DE
- 代理机构： Laudien, Dieter, Dr.
- 优先权： DE19911509 19990315
- 国际公布： WO0055141 20000921
- 主分类号： C07D239/94
- IPC分类号： C07D239/94 ; C07D215/54 ; C07D401/12 ; C07D413/12 ; C07D405/12 ; A61K31/517 ; A61P35/00
摘要：
The present invention relates to bicyclic heterocyclic compounds of general formula (I), wherein Ra to Rd, A to D and X are defined as in claims 1 to 8, the tautomers, stereoisomers and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases which have valuable pharmacological properties, particularly an inhibitory effect on signal transduction mediated by tyrosine kinases, their use in treating diseases, particularly tumour diseases, diseases of the lung and airways and the preparation thereof.
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