发明公开
EP1164192A1 SORBITOL DEHYDROGENASE, GENE ENCODING THE SAME AND USE THEREOF
审中-公开
SORBITOL-DEHYDROGENASE，DAFüRKODIERENDES GEN UND DEREN VERWENDUNG
- 专利标题： SORBITOL DEHYDROGENASE, GENE ENCODING THE SAME AND USE THEREOF
- 专利标题（中）： SORBITOL-DEHYDROGENASE，DAFüRKODIERENDES GEN UND DEREN VERWENDUNG
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申请号： EP00909679.3申请日： 2000-03-16
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公开(公告)号： EP1164192A1公开(公告)日： 2001-12-19
- 发明人: SHIBATA, Takashi , ICHIKAWA, Chiyo , MATSUURA, Mitsutaka , NOGUCHI, Yuji , SAITO, Yoshimasa , YAMASHITA, Michio , TAKATA, Yoko
- 申请人： FUJISAWA PHARMACEUTICAL CO., LTD.
- 申请人地址： 4-7, Doshomachi 3-chome Chuo-ku Osaka-shi Osaka 541-8514 JP
- 专利权人： FUJISAWA PHARMACEUTICAL CO., LTD.
- 当前专利权人： FUJISAWA PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： 4-7, Doshomachi 3-chome Chuo-ku Osaka-shi Osaka 541-8514 JP
- 代理机构： Gille Hrabal Struck Neidlein Prop Roos
- 优先权： JP7281099 19990317; JP22467999 19990806
- 国际公布： WO0055329 20000921
- 主分类号： C12N15/53
- IPC分类号： C12N15/53 ; C12N9/04 ; C12N1/21 ; C12P19/02 ; C12P7/60
摘要：
The present invention provide a gene encoding D-sorbitol dehydrogenase (SLDH), a method for producing SLDH by culture of a host cell transformed with a vector expressing this gene and a method for producing L-sorbose or 2-keto-L-gulonic acid (2KLGA) using the culture. 2KLGA is an important intermediate for the production of L-ascorbic acid. Therefore, the present invention also provides a method for producing L-ascorbic acid from the 2KLGA obtained by the above-mentioned method.
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