发明公开
EP1165519A1 ARYL AND HETEROARYL FUSED AMINOALKYL-IMIDAZOLE DERIVATIVES AND THEIR USE AS ANTIDIABETICS
审中-公开
芳基和杂凝聚AMINOALKYLIMIDAZOLDERIVATE及其作为抗糖尿病
- 专利标题： ARYL AND HETEROARYL FUSED AMINOALKYL-IMIDAZOLE DERIVATIVES AND THEIR USE AS ANTIDIABETICS
- 专利标题（中）： 芳基和杂凝聚AMINOALKYLIMIDAZOLDERIVATE及其作为抗糖尿病
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申请号： EP00919947.2申请日： 2000-03-31
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公开(公告)号： EP1165519A1公开(公告)日： 2002-01-02
- 发明人: DESIMONE, Robert, W. , HUTCHISON, Alan
- 申请人： NEUROGEN CORPORATION
- 申请人地址： 35 N.E. Industrial Road Branford, CT 06405 US
- 专利权人： NEUROGEN CORPORATION
- 当前专利权人： NEUROGEN CORPORATION
- 当前专利权人地址： 35 N.E. Industrial Road Branford, CT 06405 US
- 代理机构： Smaggasgale, Gillian Helen
- 优先权： US127656P 19990402; US285415 19990402
- 国际公布： WO0059887 20001012
- 主分类号： C07D235/14
- IPC分类号： C07D235/14 ; C07D471/04 ; A61K31/4184 ; A61K31/4188 ; A61P3/10 ; G01N33/50
摘要：
Disclosed are compounds of formula (I) or the pharmaceutically acceptable non-toxic salts thereof wherein X, R1, R2, R3, R4, R5, R6, R7, A, B, C, and D are variables defined herein. Such compounds useful in treatment of obesity and diabetes. The invention also provides labeled probes for the localization of cellular receptors that are involved in the modulation of blood glucose levels.
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