发明公开
EP1178952A1 NOVEL INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR-$g(a) MODULATORS, SYNTHESES OF SAID MODULATORS AND METHODS OF USING SAID MODULATORS
有权
白细胞介素-1和肿瘤坏死因子α调节剂，合成该调制器和本调制器的应用方法
- 专利标题： NOVEL INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR-$g(a) MODULATORS, SYNTHESES OF SAID MODULATORS AND METHODS OF USING SAID MODULATORS
- 专利标题（中）： 白细胞介素-1和肿瘤坏死因子α调节剂，合成该调制器和本调制器的应用方法
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申请号： EP00932408.8申请日： 2000-05-12
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公开(公告)号： EP1178952A1公开(公告)日： 2002-02-13
- 发明人: PALLADINO, Michael , THEODORAKIS, Emmanuel, A.
- 申请人： Nereus Pharmaceuticals, Inc. , The Regents of the University of California
- 申请人地址： Suite 210, 9393 Towne Center Drive San Diego, CA 92121 US
- 专利权人： Nereus Pharmaceuticals, Inc.,The Regents of the University of California
- 当前专利权人： Nereus Pharmaceuticals, Inc.,The Regents of the University of California
- 当前专利权人地址： Suite 210, 9393 Towne Center Drive San Diego, CA 92121 US
- 代理机构： Van Malderen, Joelle
- 优先权： US134295P 19990514; US186853P 20000303
- 国际公布： WO0073253 20001207
- 主分类号： C07C61/35
- IPC分类号： C07C61/35 ; C07C61/29 ; C07C69/753 ; C07C69/757 ; C07C69/007 ; C07C69/00 ; C07C33/14 ; C07C13/60 ; A61K31/22 ; A61K31/215 ; A61K31/19 ; A61K31/045 ; A61K31/015
摘要：
Compounds are disclosed that have the chemical structure of Formula (II) and (IIB) and their produg esters and acid-addition salts, and that are useful as Interleukin-1 and Tumor Necrosis Factor-a modulators, and thus are useful in the treatment of various diseases, wherein the R groups are defined in the claims.
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