发明公开
- 专利标题: IL-8 RECEPTOR ANTAGONISTS
- 专利标题(中): IL-8受体拮抗剂
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申请号: EP00942843申请日: 2000-06-15
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公开(公告)号: EP1185261A4公开(公告)日: 2004-02-25
- 发明人: BENSON GREGORY MARTIN , HERTZBERG ROBERT P , JUREWICZ ANTHONY J , RUTLEDGE MELVIN CLARENCE , VEBER DANIEL F , WIDDOWSON KATHERINE L
- 申请人: SMITHKLINE BEECHAM CORP
- 专利权人: SMITHKLINE BEECHAM CORP
- 当前专利权人: SMITHKLINE BEECHAM CORP
- 优先权: US13967599 1999-06-16
- 主分类号: C07D317/58
- IPC分类号: C07D317/58 ; A61K31/17 ; A61K31/18 ; A61K31/235 ; A61K31/27 ; A61K31/275 ; A61K31/36 ; A61K31/381 ; A61K31/426 ; A61K31/47 ; A61P1/02 ; A61P7/00 ; A61P9/10 ; A61P19/10 ; A61P31/16 ; A61P31/20 ; A61P33/06 ; A61P43/00 ; C07D215/36 ; C07D277/20 ; C07D277/52 ; C07D333/34 ; C07D333/36 ; A61K31/277
摘要:
This invention provides for a method of treating a chemokine mediated disease, wherein the chemokine is one which binds to an IL-8 alpha or beta receptor and which method comprises administering an effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof. In particular the chemokine is IL-8.
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