发明公开
EP1187628A2 METABOLIC INTERVENTION WITH GLP-1 OR ITS BIOLOGICALLY ACTIVE ANALOGUES TO IMPROVE THE FUNCTION OF THE ISCHEMIC AND REPERFUSED BRAIN
有权
用GLP-1或他的生物活性类似物代谢介入以改善缺血性和功能块再次脑灌注
- 专利标题: METABOLIC INTERVENTION WITH GLP-1 OR ITS BIOLOGICALLY ACTIVE ANALOGUES TO IMPROVE THE FUNCTION OF THE ISCHEMIC AND REPERFUSED BRAIN
- 专利标题(中): 用GLP-1或他的生物活性类似物代谢介入以改善缺血性和功能块再次脑灌注
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申请号: EP00928616.2申请日: 2000-05-01
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公开(公告)号: EP1187628A2公开(公告)日: 2002-03-20
- 发明人: COOLIDGE, Thomas, R. , EHLERS, Mario, R., W.
- 申请人: BIONEBRASKA, INC.
- 申请人地址: 3820 N.W. 46th Street Lincoln, NB 68524 US
- 专利权人: BIONEBRASKA, INC.
- 当前专利权人: BIONEBRASKA, INC.
- 当前专利权人地址: 3820 N.W. 46th Street Lincoln, NB 68524 US
- 代理机构: Thomson, Paul Anthony
- 优先权: US303016 19990430
- 国际公布: WO0066142 20001109
- 主分类号: A61K38/26
- IPC分类号: A61K38/26 ; A61P9/10
摘要:
It has now been discovered that GLP-1 treatment after acute stroke or hemorrhage, preferably intravenous administration, can be an ideal treatment because it provides a means for optimizing insulin secretion, increasing brain anabolism, enhancing insulin effectiveness by suppressing glucagon, and maintaining euglycemia or mild hypoglycemia with no risk of severe hypoglycemia.
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