发明公开
- 专利标题： ADJUVANT COMPOSITION COMPRISING SAPONIN AND AN IMMUNOSTIMULATORY OLIGONUCLEOTIDE
- 专利标题（中）： 佐剂组合物含皂素的免疫刺激寡核苷酸
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申请号： EP00920647.5申请日： 2000-04-04
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公开(公告)号： EP1187629A2公开(公告)日： 2002-03-20
- 发明人: FRIEDE, Martin,SmithKline Beecham Biologicals SA , GARCON, Nathalie , HERMAND, Philippe
- 申请人： SmithKline Beecham Biologicals s.a.
- 申请人地址： Rue de l'Institut 89 1330 Rixensart BE
- 专利权人： SmithKline Beecham Biologicals s.a.
- 当前专利权人： SmithKline Beecham Biologicals s.a.
- 当前专利权人地址： Rue de l'Institut 89 1330 Rixensart BE
- 代理机构： Easeman, Richard Lewis
- 优先权： GB9908885 19990419; US301829 19990429
- 国际公布： WO0062800 20001026
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/39 ; A61P31/04 ; A61P31/12 ; A61P35/00 ; A61P37/08 ; A61P25/28
摘要：
The present invention relates to adjuvant compositions which are suitable to be used in vaccines. In particular, the adjuvant compositions of the present invention comprises a saponin and an immunostimulatory oligonucleotide, optionally with a carrier. Also provided by the present invention are vaccines comprising the adjuvants of the present invention and an antigen. Further provided are methods of manufacture of the adjuvants and vaccines of the present invention and their use as medicaments. Methods of treating an individual susceptible to or suffering from a disease by the administration of the vaccines of the present invention are also provided.
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