公开(公告)号：EP1187629A2

公开(公告)日：2002-03-20

申请号：EP00920647.5

申请日：2000-04-04

申请人： SmithKline Beecham Biologicals s.a.

发明人： FRIEDE, Martin,SmithKline Beecham Biologicals SA ,  GARCON, Nathalie ,  HERMAND, Philippe

IPC分类号： A61K39/00 ,  A61K39/39 ,  A61P31/04 ,  A61P31/12 ,  A61P35/00 ,  A61P37/08 ,  A61P25/28

CPC分类号： A61K39/39 ,  A61K39/0011 ,  A61K2039/55505 ,  A61K2039/55555 ,  A61K2039/55561 ,  A61K2039/55566 ,  A61K2039/55577 ,  A61K2039/55583 ,  A61K2039/6068 ,  Y02A50/386 ,  Y02A50/412

摘要： The present invention relates to adjuvant compositions which are suitable to be used in vaccines. In particular, the adjuvant compositions of the present invention comprises a saponin and an immunostimulatory oligonucleotide, optionally with a carrier. Also provided by the present invention are vaccines comprising the adjuvants of the present invention and an antigen. Further provided are methods of manufacture of the adjuvants and vaccines of the present invention and their use as medicaments. Methods of treating an individual susceptible to or suffering from a disease by the administration of the vaccines of the present invention are also provided.