发明公开
- 专利标题: PHENOXYPROPYLAMINE COMPOUNDS
- 专利标题(中): PHENOXYPROPYLAMIN衍
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申请号: EP00927844申请日: 2000-05-22
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公开(公告)号: EP1188747A4公开(公告)日: 2002-10-09
- 发明人: NISHIYAMA AKIRA , BOUGAUCHI MASAHIRO , KUROITA TAKANOBU , MINOGUCHI MASANORI , MORIO YASUNORI , KANZAKI KOUJI
- 申请人: MITSUBISHI PHARMA CORP
- 专利权人: MITSUBISHI PHARMA CORP
- 当前专利权人: MITSUBISHI PHARMA CORP
- 优先权: JP14275099 1999-05-24; JP16616099 1999-06-14; JP27738499 1999-09-29; JP2000018080 2000-01-25
- 主分类号: A61P1/00
- IPC分类号: A61P1/00 ; A61P9/00 ; A61P25/00 ; A61P25/24 ; A61P43/00 ; C07D209/42 ; C07D401/12 ; C07D401/14 ; C07D405/12 ; C07D405/14 ; C07D409/12 ; C07D409/14 ; C07D413/04 ; C07D413/12 ; C07D413/14 ; C07D417/12 ; C07D417/14 ; C07D491/10 ; C07D491/107 ; A61K31/445 ; C07D207/36 ; C07D233/96 ; C07D263/22 ; C07D307/33 ; C07D307/46
摘要:
Phenoxypropylamine compounds represented by general formula (I), optically active isomers thereof or pharmaceutically acceptable salts thereof and hydrates of the same which have an affinity selectively for 5-HT1A receptor, simultaneously show an antagonistic activity, and inhibit the reuptake of 5-HT, thereby being usable as antidepressant agents quickly achieving an antidepressant effect wherein each symbol is as defined in the description.
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