发明公开
- 专利标题: PROSTASE VACCINE
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申请号: EP00947977.5申请日: 2000-07-11
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公开(公告)号: EP1194571A1公开(公告)日: 2002-04-10
- 发明人: CABEZON SILVA, Teresa , DILLON, Davin Clifford
- 申请人: SMITHKLINE BEECHAM BIOLOGICALS S.A. , CORIXA CORPORATION
- 申请人地址: 89 rue de l'Institut 1330 Rixensart BE
- 专利权人: SMITHKLINE BEECHAM BIOLOGICALS S.A.,CORIXA CORPORATION
- 当前专利权人: SMITHKLINE BEECHAM BIOLOGICALS S.A.,CORIXA CORPORATION
- 当前专利权人地址: 89 rue de l'Institut 1330 Rixensart BE
- 代理机构: Dalton, Marcus Jonathan William
- 优先权: US352616 19990713; US439313 19991112; US443686 19991118; US483672 20000114; US536857 20000327; US568100 20000509; US570737 20000512; US593793 20000613; GB0015747 20000627; US605783 20000627
- 国际公布: WO0104143 20010118
- 主分类号: C12N15/62
- IPC分类号: C12N15/62 ; C07K19/00 ; C12N1/21 ; A61K39/00 ; A61K31/70
摘要:
The present invention relates to novel proteins and to their production, from the prostase family. In particular, the invention pertains to a prostase protein or fragment thereof fused to an immunological fusion partner, such as NS1. Such antigens may be formulated to provide vaccines for the treatment of prostate tumours. Novel methods for purifying prostase protein and homologues are also provided.
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