发明公开
- 专利标题： METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS AND THEIR USE FOR TREATING CENTRAL NERVOUS SYSTEM DISEASES
- 专利标题（中）： 为中央神经系统疾病的治疗代谢型谷氨酸受体拮抗剂
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申请号： EP00936465.4申请日： 2000-06-02
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公开(公告)号： EP1196397A1公开(公告)日： 2002-04-17
- 发明人: VAN WAGENEN, Bradford, C. , MOE, Scott, T. , SMITH, Daryl, L. , SHEEHAN, Susan, M. , SHCHERBAKOVA, Irina , TRAVATO, Richard , WALTON, Ruth , BARMORE, Robert , DELMAR, Eric, G. , STORMANN, Thomas, M.
- 申请人： NPS PHARMACEUTICALS, INC.
- 申请人地址： Suite 240,420 Chipeta Way Salt Lake CityUtah 84108 US
- 专利权人： NPS PHARMACEUTICALS, INC.
- 当前专利权人： NPS PHARMACEUTICALS, INC.
- 当前专利权人地址： Suite 240,420 Chipeta Way Salt Lake CityUtah 84108 US
- 代理机构： Plougmann, Vingtoft & Partners A/S
- 优先权： US137272P 19990602
- 国际公布： WO0073283 20001207
- 主分类号： C07D241/44
- IPC分类号： C07D241/44 ; C07D215/54 ; C07D209/42 ; C07D213/82 ; C07D307/68 ; C07D307/84 ; C07D333/38 ; C07D333/68 ; A61K31/495 ; A61K31/404 ; A61P25/00
摘要：
The present invention provides compounds, and pharmaceutical compositions containing those compounds, that are active at metabotropic glutamate receptors. The compounds are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.
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