发明授权
EP1198476B1 DEATH EFFECTOR DOMAIN OF MAMMALIAN APOPTOSIS MEDIATOR, FADD, INDUCING BACTERIAL CELL DEATH
有权
“死亡效应”哺乳动物细胞凋亡介体结构域,FADD,细菌细胞死亡触发器
- 专利标题: DEATH EFFECTOR DOMAIN OF MAMMALIAN APOPTOSIS MEDIATOR, FADD, INDUCING BACTERIAL CELL DEATH
- 专利标题(中): “死亡效应”哺乳动物细胞凋亡介体结构域,FADD,细菌细胞死亡触发器
-
申请号: EP00942486.2申请日: 2000-07-11
-
公开(公告)号: EP1198476B1公开(公告)日: 2006-09-06
- 发明人: KIM, Sunghoon , KIM, Key-Sun
- 申请人: Imagene Co., Ltd. , Korea Institute of Science and Technology
- 申请人地址: 8F Daedong B/D, 1306-8 Seocho-dong Seocho-ku, Seoul 137-070 KR
- 专利权人: Imagene Co., Ltd.,Korea Institute of Science and Technology
- 当前专利权人: Imagene Co., Ltd.,Korea Institute of Science and Technology
- 当前专利权人地址: 8F Daedong B/D, 1306-8 Seocho-dong Seocho-ku, Seoul 137-070 KR
- 代理机构: Prato, Roberto
- 优先权: KR9927964 19990712
- 国际公布: WO2001004153 20010118
- 主分类号: C07K14/47
- IPC分类号: C07K14/47 ; C12N15/62 ; C12Q1/68
摘要:
The present invention relates to a death effector domain, FADD-DED (SEQ ID NO: 3) of mammalian apoptosis mediator, FADD (SEQ ID NO: 2) encoded by cDNA clone (SEQ ID NO: 1), wherein FADD-DED induces baterial cell death as well as mammalian cell death by enhancing cellular level of Reactive Oxygen Species (ROS).
公开/授权文献
信息查询