发明公开
EP1202734A1 3(5)-UREIDO-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS
有权
3（5） - 脲基 - 吡唑衍生物，它们的制备方法和用途作为抗癌药
- 专利标题： 3(5)-UREIDO-PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR AGENTS
- 专利标题（中）： 3（5） - 脲基 - 吡唑衍生物，它们的制备方法和用途作为抗癌药
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申请号： EP00955241.5申请日： 2000-08-11
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公开(公告)号： EP1202734A1公开(公告)日： 2002-05-08
- 发明人: PEVARELLO, Paolo , ORSINI, Paolo , TRAQUANDI, Gabriella , VARASI, Mario , FRITZEN, Edward, L. , WARPEHOSKI, Martha, A. , PIERCE, Betsy, S.
- 申请人： Pharmacia Italia S.p.A. , PHARMACIA & UPJOHN COMPANY
- 申请人地址： Via Robert Koch 1.2 20152 Milano IT
- 专利权人： Pharmacia Italia S.p.A.,PHARMACIA & UPJOHN COMPANY
- 当前专利权人： Pharmacia Italia S.p.A.,PHARMACIA & UPJOHN COMPANY
- 当前专利权人地址： Via Robert Koch 1.2 20152 Milano IT
- 优先权： US372833 19990812
- 国际公布： WO0112188 20010222
- 主分类号： A61K31/415
- IPC分类号： A61K31/415 ; A61K31/496 ; C07D231/40 ; C07D403/12
摘要：
3-ureido-pyrazole derivatives represented by formula (I): where R, R1 and R2 are as described herein, or pharmaceutically acceptable salts thereof; are useful, for example, for the treatment of cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases or neurodegenerative diseases.
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