发明公开
EP1206442A1 SUBSTITUTED CHIRAL ALLOSTERIC HEMOGLOBIN MODIFIERS
审中-公开
SUITTITERERTE CHIRALE ALLOSTERISCHEHÄMOGLOBINMODIFIZIERENDE MITTEL
- 专利标题: SUBSTITUTED CHIRAL ALLOSTERIC HEMOGLOBIN MODIFIERS
- 专利标题(中): SUITTITERERTE CHIRALE ALLOSTERISCHEHÄMOGLOBINMODIFIZIERENDE MITTEL
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申请号: EP00955827.1申请日: 2000-08-23
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公开(公告)号: EP1206442A1公开(公告)日: 2002-05-22
- 发明人: ABRAHAM, Donald, J. , JOSHI, Gajanan, S. , HOFFMAN, Stephen, J. , GRELLA, Melissa , DANSO-DANQUAH, Richmond , YOUSSEF, Amal , SAFO, Martin , KULKARNI, Sanjeev
- 申请人: VIRGINIA COMMONWEALTH UNIVERSITY , Allos Therapeutics, Inc.
- 申请人地址: 1101 East Marshall Street Richmond, VA 23298 US
- 专利权人: VIRGINIA COMMONWEALTH UNIVERSITY,Allos Therapeutics, Inc.
- 当前专利权人: VIRGINIA COMMONWEALTH UNIVERSITY,Allos Therapeutics, Inc.
- 当前专利权人地址: 1101 East Marshall Street Richmond, VA 23298 US
- 代理机构: Lins, Edgar, Dipl.-Phys. Dr.jur.
- 优先权: US150351P 19990824; US176635P 20000119
- 国际公布: WO0114316 20010301
- 主分类号: C07C229/02
- IPC分类号: C07C229/02 ; C07C229/50 ; C07C309/08 ; C07C311/02
摘要:
A family of substituted chiral allosteric effectors of hemoglobin is useful for delivering more oxygen to hypoxic and ischemic tissues by reducing the oxygen affinity of hemoglobin in whole blood.
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