发明公开
EP1230268A2 HETEROCLITIC ANALOGS OF CLASS I EPITOPES
有权
HETEROKLITISCHE ANALOGA VON KLASSE-I EPITOPEN
- 专利标题: HETEROCLITIC ANALOGS OF CLASS I EPITOPES
- 专利标题(中): HETEROKLITISCHE ANALOGA VON KLASSE-I EPITOPEN
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申请号: EP00979208.6申请日: 2000-11-20
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公开(公告)号: EP1230268A2公开(公告)日: 2002-08-14
- 发明人: TANGRI, Shabnam , SETTE, Alessandro , ISHIOKA, Glenn
- 申请人: Epimmune, Inc.
- 申请人地址: Suite 100,5820 Nancy Ridge Drive San Diego,California 92121 US
- 专利权人: Epimmune, Inc.
- 当前专利权人: Epimmune, Inc.
- 当前专利权人地址: Suite 100,5820 Nancy Ridge Drive San Diego,California 92121 US
- 代理机构: Baldock, Sharon Claire
- 优先权: US166529P 19991118; US239008P 20001006
- 国际公布: WO0136452 20010525
- 主分类号: C07K14/705
- IPC分类号: C07K14/705 ; C07K7/06 ; A61K39/00
摘要:
Heteroclitic analogs of Class I epitopes are prepared by providing conservative or semi-conservative amino acid substitutions at positions 3 and/or 5 and/or 7 of these epitopes. The analogs are useful in eliciting immune responses with respect to the corresponding wildtype epitopes.
公开/授权文献
- EP1230268B1 HETEROCLITIC ANALOGS OF CLASS I EPITOPES 公开/授权日:2009-10-14
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