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1.发明授权INDUCING IMMUNE RESPONSES TO INFLUENZA VIRUS USING POLYPEPTIDE AND NUCLEIC ACID COMPOSITIONS 有权免疫反应诱导流感病毒和使用POLYPEPITD-核酸组合物
公开(公告)号：EP2023952B1
公开(公告)日：2015-07-15
申请号：EP07867125.2
申请日：2007-05-18
申请人： Epimmune Inc.
CPC分类号： A61K39/145 , A61K39/12 , A61K39/385 , A61K39/39 , A61K2039/53 , A61K2039/545 , A61K2039/55505 , A61K2039/55566 , A61K2039/605 , A61K2039/627 , C07K14/005 , C12N2760/16122 , C12N2760/16134
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2.发明授权
公开(公告)号：EP1078092B1
公开(公告)日：2011-08-03
申请号：EP99924233.2
申请日：1999-05-13
申请人： Epimmune Inc.
发明人： FIKES, John, D. , HERMANSON, Gary, G. , SETTE, Alessandro , ISHIOKA, Glenn Y. , LIVINGSTON, Brian , CHESNUT, Robert, W.
IPC分类号： C12N15/85
CPC分类号： C07K14/70539 , A01K2217/05 , A61K38/00 , A61K39/385 , A61K2039/605 , C07K14/005 , C07K14/445 , C07K2319/00 , C07K2319/02 , C12N2730/10122 , C12N2740/16122 , C12N2740/16222 , C12N2740/16322 , C12N2770/24222 , Y02A50/412
摘要： The present invention relates to nucleic acid vaccines encoding multiple CTL and HTL epitopes and MHC targeting sequences.
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3.发明公开METHOD AND SYSTEM FOR OPTIMIZING MULTI-EPITOPE NUCLEIC ACID CONSTRUCTS AND PEPTIDES ENCODED THEREBY 有权FOR NUCLEIC优化方法和制度，多个表位并将此内存肽构建
公开(公告)号：EP1521963A4
公开(公告)日：2008-05-28
申请号：EP02725433
申请日：2002-03-28
申请人： EPIMMUNE INC
发明人： SETTE ALESSANDRO , CHESNUT ROBERT , LIVINGSTON BRIAN D , BAKER DENISE MARIE , NEWMAN MARK J , BROWN DAVID H
IPC分类号： C12N15/09 , A61K39/00 , A61K39/21 , A61K39/29 , A61K39/295 , A61K48/00 , A61P43/00 , C07K14/115 , C07K14/16 , C12N15/86 , G06F17/50 , G06F19/16 , G06F19/18 , G06F19/22 , G06F19/24 , G01N33/53 , G06F19/00 , G06G7/58
CPC分类号： A61K39/29 , A61K39/00 , A61K39/12 , A61K39/21 , A61K39/292 , A61K2039/53 , A61K2039/54 , A61K2039/545 , A61K2039/57 , A61K2039/70 , C07K14/005 , C07K2319/00 , C12N15/86 , C12N2730/10122 , C12N2730/10134 , C12N2740/16022 , C12N2740/16034 , G06F19/16 , G06F19/18 , G06F19/22 , G06F19/24
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4.发明公开
公开(公告)号：EP1767542A2
公开(公告)日：2007-03-28
申请号：EP05075377.1
申请日：1997-03-21
申请人： Epimmune Inc.
发明人： Grey, Howard M , Sette, Alessandro , Sidney, John
CPC分类号： C07K14/005 , A61K39/00 , C12N2730/10122 , C12N2740/16122 , C12N2740/16222 , C12N2740/16322 , C12N2770/24222
摘要： Peptides of antigens of HCV and HBV are disclosed, together with nucleotides encoding the peptides. The peptides may be used in the treatment or prevention of HCV or HBV infection.
摘要翻译： 公开了HCV和HBV抗原的肽以及编码肽的核苷酸。 肽可用于治疗或预防HCV或HBV感染。
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公开(公告)号：EP1455816A4
公开(公告)日：2007-03-28
申请号：EP01274676
申请日：2001-10-18
申请人： EPIMMUNE INC
发明人： SETTE ALESSANDRO , SIDNEY JOHN , SOUTHWOOD SCOTT
IPC分类号： A61K39/385 , A61K39/00
CPC分类号： A61K39/385 , A61K2039/5154 , A61K2039/5158 , A61K2039/605
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6.发明公开INDUCING CELLULAR IMMUNE RESPONSES TO HEPATITIS C VIRUS USING PEPTIDE AND NUCLEIC ACID COMPOSITIONS 审中-公开肽核酸化合物用于释放的细胞免疫应答丙型肝炎USE
公开(公告)号：EP1200109A4
公开(公告)日：2005-06-15
申请号：EP00948819
申请日：2000-07-19
申请人： EPIMMUNE INC
发明人： SETTE ALESSANDRO , SIDNEY JOHN , SOUTHWOOD SCOTT , LIVINGSTON BRIAN D , CHESNUT ROBERT , BAKER DENISE MARIE , CELIS ESTEBAN , KUBO RALPH T , GREY HOWARD M
IPC分类号： A61K9/127 , A61K38/00 , A61K38/11 , A61K39/00 , A61K39/295 , A61K47/44 , A61K47/48 , A61P1/16 , A61P31/14 , A61P37/02 , C07K14/18 , A61K38/04 , A61K38/08 , A61K38/10 , A61K39/29
CPC分类号： C07K14/005 , A61K38/00 , A61K39/00 , A61K2039/70 , C07K2319/00 , C12N2770/24222
摘要： This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to identify and prepare HCV epitopes, and to develop epitope-based vaccines directed towards HCV. More specifically, this application communicates our discovery of pharmaceutical compositions and methods of use in the prevention and treatment of HCV infection.
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公开(公告)号：EP1189624A4
公开(公告)日：2005-02-23
申请号：EP00944976
申请日：2000-06-28
申请人： EPIMMUNE INC
发明人： SETTE ALESSANDRO , SIDNEY JOHN , SOUTHWOOD SCOTT
IPC分类号： A61K39/00 , A61K38/00 , A61P31/12 , A61P35/00 , C07K7/06 , C07K14/47 , A61K38/04 , A01N63/00 , A61K38/08 , A61K38/10
摘要： The present invention provides the means and methods for selecting immunogenic peptides and the immunogenic peptide compositions capable of specifically binding glycoproteins encoded by HLA alleles and inducing T cell activation in T cells restricted by the allele. The peptides are useful to elicit an immune response against a desired antigen.
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公开(公告)号：EP1455816A2
公开(公告)日：2004-09-15
申请号：EP01274676.4
申请日：2001-10-18
申请人： Epimmune Inc.
IPC分类号： A61K39/00
CPC分类号： A61K39/385 , A61K2039/5154 , A61K2039/5158 , A61K2039/605
摘要： The present invention provides the means and methods for selecting immunogenic peptides and the immunogenic peptide compositions capable of specifically binding glycoproteins encoded by HLA alleles and inducing T cell activation in T cells restricted by the allele. The peptides are useful to elicit an immune response against a desired antigen.
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公开(公告)号：EP1320377A1
公开(公告)日：2003-06-25
申请号：EP00961444.7
申请日：2000-09-01
申请人： Epimmune Inc.
IPC分类号： A61K38/03
CPC分类号： C07K14/005 , C07K14/445 , C07K14/4746 , C07K14/4748 , C07K14/71 , C12N2730/10122 , C12N2740/16122 , C12N2740/16222 , C12N2740/16322 , C12N2770/24222 , Y02A50/412
摘要： The present invention provides peptide compositions capable of binding glycoproteins encoded by HLA, HLA-B, and HLA-C alleles and inducing T cell activation in T cells restricted by the HLA allele. The peptides are useful to elicit an immune response against a desired antigen.
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公开(公告)号：EP1263775A1
公开(公告)日：2002-12-11
申请号：EP00910314.4
申请日：2000-02-23
申请人： Epimmune, Inc.
CPC分类号： C07K7/06 , A61K38/00 , A61K39/00 , A61K2039/57
摘要： The present invention provides the means and methods for selecting immunogenic peptides and the immunogenic peptide compositions capable of specifically binding glycoproteins encoded by HLA alleles and inducing T cell activation in T cells restricted by the allele. The peptides are useful to elicit an immune response against a desired antigen.
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